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old man portrait head hands face wrinkles expression emotion mood thoughtful contemplative melancholy sadness sorrow grief despair hopelessness loneliness isolation vulnerability frailty aging decline deterioration decay ruin destruction death mortality impermanence vanity transience fugacity elusiveness imperceptibility insignificance nothingness void emptiness meaninglessness absurdity pointlessness hopelessness despair desolation forlornness abandonment rejection neglect indifference apathy ennui boredom tedium monotony routine sameness predictability banality mediocrity unremarkableness insignificance inconsequentiality triviality pettiness paltriness meanness shabbiness squalor dirt grime filth ugliness deformity grotesqueness monstrosity hideousness repulsiveness loathsomeness disgustingness nauseatingness sickness disease illness injury wound sore boil abscess tumor cancer growth malignant benign metastasis spread incurable terminal fatal deadly lethal mortal dying death demise passing expiration 終結 消滅 毀滅 死亡 終結 消滅 毀滅 死亡