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woman face hands portrait painting oil painting canvas art expression emotion melancholy sadness sorrow grief despair hopelessness anguish torment agony suffering misery unhappiness unjoy depression mental health illness disease disorder problem issue challenge struggle battle fight war conflict turmoil chaos upset disturbance disruption break breakdown collapse failure defeat loss damage harm injury pain suffering anguish torment agony misery unhappiness unjoy depression mental health illness disease disorder problem issue challenge struggle battle fight war conflict turmoil chaos upset disturbance disruption break breakdown collapse failure defeat loss damage harm injury pain